Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.

نویسندگان

  • Yuichi Tambo
  • Masaki Fujimura
  • Masahide Yasui
  • Kazuo Kasahara
  • Yasuto Nakatsumi
  • Shinji Nakao
چکیده

A 72 year-old man. He was diagnosed with rheumatoid arthritis in 2002. In January 2005 he noted productive cough and fever; he was diagnosed as eosinophilic pneumonia (EP). We discontinued administration of bucillamine and methotrexate and started to treat with oral prednisolone 30 mg daily. To rule out drug-induced EP, prednisolone was tapered by 10 mg per week. Consolidation occurred in the right lower lobe when prednisolone was decreased to 5 mg daily. After increasing the dose of prednisolone to 30 mg daily again, consolidation was promptly resolved. It was considered to be important to rule out drug-induced EP.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Eosinophilic Pneumonia Associated with Rheumatoid Arthritis: Description of a Case Report and Review of the Literature

Rheumatoid arthritis, a systemic inflammatory disease, may induce pulmonary manifestations. We describe a case of longstanding RA presenting with eosinophilic pneumonia. Rare case reports of tissue eosinophilia involving isolated organs in the setting of rheumatoid arthritis exist in the literature. It has been shown that the production of proinflammatory cytokines activates different cell grou...

متن کامل

Chronic eosinophilic pneumonia complicating long-standing rheumatoid arthritis.

A 54-year-old patient with long-standing rheumatoid arthritis developed chronic eosinophilic pneumonia in association with a relapse of his arthritic condition. There was a rapid and complete response to oral steroid therapy.

متن کامل

Chronic eosinophilic pneumonia: autoimmune phenomenon or immunoallergic disease? Case report and literature review.

Eosinophilic pneumonia is classified by its acute or chronic presentation, the distinguishing characteristics of which are based on the presence of cough, dyspnea, fever and pulmonary infiltrates with accumulation of inflammatory cells, predominantly eosinophils. The association of eosinophilia and rheumatologic disorders is well known, as in the case of eosinophilic fasciitis and the Churg-Str...

متن کامل

Increased serum ADAM8 concentration in patients with drug-induced eosinophilic pneumonia-ADAM8 expression depends on a the allergen route of entry.

BACKGROUND ADAM8 (a disintegrin and a metalloprotease 8) has been linked to asthma and eosinophilic pneumonia (EP). ADAM8 cleaves a variety of substrates and is a sheddase for CD23, the low affinity IgE receptor. The concentration of soluble ADAM8 (sADAM8) is increased in bronchoalveolar lavage fluid (BALF) from patients with smoking-induced acute eosinophilic pneumonia (AEP) and chronic eosino...

متن کامل

Chronic eosinophilic pneumonia in a breast cancer patient post-radiation therapy: a case report.

Chronic eosinophilic pneumonia (CEP) is a syndrome associated with nonspecific pulmonary and atopic manifestations, chest imaging findings suggestive of peripheral alveolar opacities, and alveolar and blood eosinophilia.1 Onset is insidious, with symptoms lasting up to 2–4 weeks. It is usually idiopathic; however, it has been associated with drugs, allergy shots, parasites, irradiation for brea...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Internal medicine

دوره 47 6  شماره 

صفحات  -

تاریخ انتشار 2008